IMPULSE (Integrated Multiscale Process Units with Locally Structured Elements) aims at effective and targeted integration of innovative process equipment. Included are microreactors, compact heat exchangers, thin-film devices and other micro and/or meso-structured components, aimed at attaining radical performance enhancement for whole process systems in chemical and pharmaceutical production. In this way it contributes to significant improvement in supply-chain sustainability for the chemical industry. IMPULSE goals include the proof of principle in major supply-chain sectors (pharmaceuticals, specialty chemicals, and consumer goods), validated business models (e.g., distributed production, mass customization, etc.), “teachable” generic design methodology and optimization and decision criteria for eco-effficiency.